High Purity in stock Amygdalin 630-56-8 good supplier CAS NO.29883-15-6

 

Jiangsu Ruda Bioengineering Co. Ltd. is a high-tech limited company was founded in Xuzhou P.R.C 2019. The company is committed to the development of pharmaceutical raw materials, intermediate production, pharmaceutical raw materials processing, management and import and export of natural plants and their extracts.  The company has a full in-house laboratory to offer assistance to customers who require product development or technical support. Ruda adheres to Standard Operating Procedures covering all aspects of the business which ensures that our facility meets the requirements and approval of multi-national manufacturers as a world class distributor.

The company has relatively high processing capability for pharmaceutical raw materials and is now producing bile acid products and a variety of Chinese herbal extracts. At the same time, the company also sells high-quality Chinese herbal medicine. 

The company constantly improved its technological advantage, capacity advantage and market advantage. The company insists on the basic expansion path of "opens up the market outward and pays great attention to the internal management".   

Focusing on innovative products and innovative services for customers in the pharmaceutical, healthcare, food and cosmetic industries. The company  has established deep relationships with large pharmaceutical and food companies in the Americas, Europe, Africa and Asia.  It will be the best supplier of Chinese herbal medicine, pharmaceutical raw materials, pharmaceutical intermediates and natural extracts supplier.

Raw Materials at Industry Standards
NWS is a leading exporter, supplier and Manufacturer for bile acids and their derivatives. We are associated with some of the most innovative companies world-wide, we assure you the highest quality and standards at competitive prices in Asia. We pride ourselves on the accuracy and reliability of our service. NWS is dedicated to delivering products and services to our customers in a timely manner that consistently meets their specifications and satisfies their expectations, by acting responsibly in all aspects of business, we aim to satisfy our customers through continuous dedication and improvement.
 

Why we are the most reliable?
NWS is staffed with experienced and dedicated employees with expertise in China Customs matters, inventory management, distribution and logistics, sales and marketing, regulatory compliance and customer service. Proficiency, high quality, reliability, and effective products range with un-interrupted supply, guaranteed on timely delivery, competitive prices and an excellent customer service. Please contact us for our services
Our company has earned ourselves a good reputation at home with advanced technologies, standardized management and a well established service system.

Process Capability :   NWS engages in the manufacture of the intermediate from animal bile, and has since been supplying a wide range of raw materials to cosmetic, nutrition and pharmaceutical industries.

 

Uses and Synthetic Methods of Amygdalin Amygdalin is a β-cyano-glycoside in the bitter almond that is bound to cyano (CN), which releases free cyano groups after eating the bitter almond, so that the food is poisoned. Amygdalin is a product of the metabolism of phenylalanine in the bitter almond. Amygdalin has β-glucosidase and amygdalinase (oxynitrilase): the former catalyzed amygdalin into two molecules of glucose and one molecule of amygdalenone through hydrolysis; the later catalyzes mandelonitrile into almond nitrile cyanide (HCN) and benzaldehyde through hydrolysis. Amygdalin exists in seeds, such as almonds.

Many plant root cells contain glycosides, with no toxic effect when in sugar type. Glycosides hydrolysis produce toxic substances leading to cell death. Mandelic glycosides contained in peach root is a glycoside. Amylose hydrolysis produce two kinds of plant toxins-hydrogen cyanide and benzaldehyde. Peeling root lesion formation and necrosis occurred in the vicinity of the stabbed nematode but not in contact zone; in addition, in vitro tests have proved that the pratylenchus penetrans can make amygdalin hydrolysis.

As a cyanide containing glucoside, it can be used as a substrate for such as maltase, almond casein and β-glucosidase identification, differentiation and characterization.

Toxicity classification Highly toxic

Acute toxicity Acute toxicity Oral-Rat LD50: 522 mg/kg; Oral-mouse LD50: 443 mg/kg

Flammability Hazardous properties Combustible; producing toxic nitrogen oxides when heated.

Storage and transportation Ventilation, low temperature, drying

Fire extinguishing agent Dry powder, foam, sand, carbon dioxide

Chemical Properties WHITE FINE CRYSTALLINE POWDER

Uses antiinflammatory, experimental antineoplastic

Definition ChEBI: An amygdalin in which the stereocentre on the cyanohydrin function has R-configuration.

World Health Organization (WHO) Laetrile, which consists mainly of amydgalin, a glycoside extracted from the kernels of apricots, peaches and other fruits, has been available for over 30 years in preparations purporting to be beneficial in the treatment of cancer. Although there is no evidence that these are efficacious, preparations continued to be widely used and, until the late 1970s, they were considered to be harmless. However, oral dosage forms, which may be broken down in the gut to hydrogen cyanide, have subsequently been shown to be potentially lethal. This has resulted in restrictive regulatory measures in several countries.

Purification Methods D-Amygdalin recrystallises from water as the trihydrate, or from EtOH. It is present in bitter almonds. [Smith Chem Ber 64 1115 1931, Beilstein 17/8 V 188.]